Research Assistant (Brenton Group) (Fixed Term)
Europe's top cancer charity, Cancer Research UK, has combined with the University of Cambridge to fund the world class Cancer Research UK Cambridge Institute, situated on the Addenbrooke's Biomedical Campus in Cambridge.
As part of the University of Cambridge, School of Clinical Medicine, the Institute's research ranges from basic cancer biology through translational cancer research to clinical application. The Institute currently houses over 350 researchers and support staff with 20 research groups and associated core facilities in a state-of-the-art research facility.
The Brenton laboratory is focused on identifying new therapeutic approaches in patients with ovarian cancer using genomic and functional studies on primary tissues and animal models.
We are looking for a Research Assistant to join our team to support a new project investigating the development of premalignant lesions in the fallopian tube using genetically engineered in vivo models of ovarian cancer. This project also involves the generation and characterization of novel syngeneic models that you will use to study micrometastasis and their interaction with the microenvironment.
You will have the opportunity to work under your own initiative and apply your excellent problem-solving skills to troubleshoot challenging technical issues. You will contribute towards running of various projects within the laboratory as well as your own project; and you will present your work regularly at lab meetings. You will assist in all aspects of the projects including: generation of genetically engineered in vivo models using CRISPR-cas9 and mammalian cell culture. You will develop wide functional experience including cell transfection, FACS, confocal microscopy, live cell imaging, as well as surgical and dissection techniques. In addition, you will assist as required in general laboratory administrative, housekeeping, and human tissue collection and processing.
Applicants will have a BSc degree/MSc in biological sciences and laboratory experience. Practical experience in in vivo studies and holding a home office personal licence to work with animals is highly desirable, but we will be delighted to consider very motivated individuals who can demonstrate excellent relevant laboratory skills. A good working knowledge of cell and molecular biology are required as are strong IT and communication skills. You should be conscientious and ambitious, with the ability to work well both independently and part of a team.
Fixed-term: The funds for this post are available for 18 months in the first instance.
Once an offer of employment has been accepted, the successful candidate will be required to undergo a basic disclosure (criminal records check) check and a security check.
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For more information about our research please see: https://www.cruk.cam.ac.uk/research-groups/brenton-group/
For informal queries regarding the post please contact Dr Matthew Ford: Matthew.Ford@cruk.cam.ac.uk
Please quote reference SW46321 on your application and in any correspondence about this vacancy.
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