Research Assistant/Research Associate (Fixed Term)
We are seeking an enthusiastic, motivated individual for a position in the group of Professor Alan Warren, Department of Hematology in the Cambridge Institute for Medical Research at the Cambridge Biomedical Campus. You will join an exciting research programme investigating fundamental mechanisms of ribosome assembly, translational control and how defects in these processes drive cancer development. This post will involve the use of cutting edge biochemical, proteomic, next generation sequencing and ribosome foot printing technologies.
This position is available for an immediate appointment. Candidates must either have a PhD in a relevant biological subject or have submitted or about to submit their PhD thesis. Candidates must also have demonstrable expertise in biochemistry, cell biology and/or molecular biology. Relevant post-doctoral experience is desirable. High quality peer-reviewed publications and a keen interest in translational regulation are essential. If you have an excellent background in biological sciences, are prepared to face intellectual challenges and wish to develop your scientific skills, we would like to hear from you. Applicants should have outstanding organisation and communication skills and work well as part of a team.
The Cambridge Institute for Medical Research (CIMR) is located on the Cambridge Biomedical Campus and it is a collaborative institute at the interface between fundamental research and the clinic, with a mission to determine the molecular mechanisms of disease in order to advance human health.
The funding for this position ends on 30th April 2030.
Applicants must have (or be close to obtaining) a PhD.
Appointment at Research Associate level is dependent on having a PhD. Those who have submitted but not yet received their PhD will initially be appointed as a Research Assistant (Grade 5, Point 36 £32,546) moving to Research Associate (Grade 7) upon confirmation of your PhD award
Research Assistant Grade 5 : £32,546 - £35,116
Research Associate Grade 7 : £37,174 - £45,413
For recent publications see below:
Machado HE, Øbro NF, Williams N, Tan S, Boukerrou AZ, Davies M, Belmonte M, Mitchell E, Baxter EJ, Mende N, Clay A, Ancliff P, Köglmeier J, Killick SB, Kulasekararaj A, Meyer S, Laurenti E, Campbell PJ, Kent DK, Nangalia J, Warren AJ. Convergent somatic evolution commences in utero in a germline ribosomopathy. Nature Communications 14, 5092 (2023). https://doi.org/10.1038/s41467-023-40896-5. PMID: 37608017
Jaako P, Faille A, Tan S, Wong CC, Escudero-Urquijo N, Castro-Hartmann P, Wright P, Hilcenko C, Adams DJ, Warren AJ. eIF6 rebinding dynamically couples ribosome maturation and translation. Nature Communications 13, 1562 2022. https://doi.org/10.1038/s41467-022-29214-7. PMID: 35322020
Tan S, Kermasson L, Hilcenko C, Kargas V, Traynor D, Boukerrou AZ, N Escudero-Urquijo, Faille A, Rossmann M, Goyenechea B, Bertrand A, Moreil J, Alibeu O, Beaupain B, Bôle-Feysot C, Fumagalli S, Kaltenbach S, Martignoles J-A, Masson C, Nitschké P, Parisot M, Pouliet A, Radford-Weiss I, Tores F, de Villartay J-P, Zarhrate M, Koh AL, Phua KB, Revesade B, Bond PJ, Bellanné-Chantelot C, Callebaut I, Delhommeau F, Donadieu J, Warren AJ* and Revy P*. Somatic genetic rescue of a germline ribosome assembly defect. Nature Communications (2021) Aug 19;12(1):5044. doi: 10.1038/s41467-021-24999-5. PMID: 34413298 *Joint Senior authors
Informal enquiries to Alan Warren ajw1000@cam.ac.uk
Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.
Closing date: 24th June 2025
Interviews will be held in mid July 2025
Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.
Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.
For information about how your personal data is used as an applicant, please see the section on Applicant Data (https://www.hr.admin.cam.ac.uk/hr-staff/hr-data/applicant-data) on our HR web pages.
Please quote reference SB46087 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.