Research Associate (Fixed Term)
Research Associate Department of Medicine - Victor Phillip Dahdaleh Heart & Lung Research Institute
Applications are invited for a Postdoctoral Research Associate, funded by the Wellcome Trust, to explore the bacterial evolution of Pseudomonas aeruginosa and Staphylococcus aureus as part of the group of Professor Andres Floto, based at the Heart Lung Research Institute, on the Cambridge Biomedical Campus. The post is available immediately for 2 years in the first instance.
Molecular bacteriology
This project will explore how bacterial determinants influence intracellular survival within macrophages and will incorporate the use of genome-wide forward genetic screening, super-resolution microscopy and novel fluorescent sensors. Candidates should have a Ph.D degree with a strong background in microbiology (ideally in Pseudomonas aeruginosa and Staphylococcus aureus) and molecular biology. Essential experience includes generating knockout, knock-in and complementary bacterial strains, cloning and expression of fluorescently tagged proteins, and standard biochemical techniques. Previous experience with mammalian cell culture and/or advanced microscopy would be advantageous, although training can be provided. Candidates should have a strong background in infection/immunology. Essential experience includes use of in vitro and in vivo bacterial infection models. This post is well suited for independent, highly motivated and creative researchers with a proven track record in molecular bacteriology and immunology respectively who wish to explore exciting biology at the interface between host and pathogen.
Applicants should send a full CV and covering letter, which should summarise their scientific interests and suitability for the role. Candidates in the process of submitting their PhD thesis or awaiting degree conferral will be considered. In this case, appointment would be at the level of Research Assistant, Grade 5. On receipt of PhD award, the appointee would move to Grade 7, Research Associate.
Informal enquiries are welcome and can be made to Professor Andres Floto at arf27@cam.ac.uk
Fixed-term: The funds for this post are available for 2 years in the first instance.
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