Applications are invited for a Senior Research Associate/Research Associate position to be based in the University of Cambridge, Department of Biochemistry, central Cambridge, working in the laboratory of Prof. Jussi Taipale. The position will be offered for an initial two years, with the potential to extend.
The laboratory consists of experimental biologists and computer scientists who focus on the study of transcriptional control of cell growth, using functional genomics and systems biology, and mouse genetic models. Current lines of work include high-throughput determination of binding sites and binding specificities of human transcription factors, and using this information to identify regulatory elements that control cell growth during normal development and in cancer (see, for example Hallikas et al., Cell 124:47-59, 2006; Sur et al., Science 338:1360-1363, 2012; Jolma et al., Cell 152:327-339, 2013; Jolma et al., Nature 527:384-388, 2015; Yin et al., Science 356:eaaj2239, 2017; Zhu et al., Nature 562:76-81, 2018; Yan et al., Nature 591:147-151, 2021; Sahu et al., Nature Genetics 54:283-294, 2022). The lab is also very well equipped with its own sequencers, 10x Genomics controller and robots for high-throughput work.
The work profile is a combination of wet-lab and dry-lab tasks. For Senior Research Associate, the work profile will involve administrative tasks, supervision of day-to-day activities of the research lab, including supervision of graduate and PhD students and lab managers. The candidate will support the PI with regard to tasks such as writing manuscripts and grant applications, reporting of grants and organizing courses and international meetings. Finally, the applicant will pursue an independent research project in the general area of gene expression and/or cancer. Candidates with experience or interest in machine learning, artificial intelligence and programming are encouraged to apply.
Applicants should have a PhD in computational biology, molecular biology, genetics, biochemistry or computational biology. Senior Research Associates should have several years of post-doctoral experience in the area. Candidate should also have experience in writing grants and supervising undergraduate, MSc and PhD students. Appointment to Senior Research Associate is subject to approval by the Faculty Board of Biochemistry.
Fixed-term: The funds for this post are available until 30 June 2024 in the first instance.
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