We have an exciting opportunity for a postdoctoral Research Associate to join our team studying the molecular mechanisms linking lysosomal dysfunction to neurodegenerative diseases. This is a Wellcome Trust-funded post in the laboratory of Dr Janet Deane at the Cambridge Institute for Medical Research. We encourage applications from scientists with a background in protein and/or lipid biochemistry who have a keen interest in developing cell-based discoveries into molecular insights.
The post holder must possess a PhD in Biochemistry, Molecular Biology or a relevant subject. Experience in protein expression and purification is essential as well as some experience with protein interaction techniques such as pulldown assays, SPR or ITC. Experience with membrane protein function or lipid biochemistry and an understanding of membrane trafficking would be advantageous.
The candidate must have a proven track record of generating publication-quality data, great attention to detail and excellent record keeping. They must also have good interpersonal skills as well as the ability to communicate their work clearly in both formal and informal settings.
The successful applicant will be part of a team with established expertise in protein purification, protein-protein and protein-lipid interaction assays, structural biology and the generation of cell-based models of disease including CRISPRi in iPSC cells. Due to the supportive nature of the laboratory enthusiastic candidates will have the oportunity to learn additional techniques and expand their research skills. Furthermore, we encourage creative thinking when tackling scientific problems and are keen for lab members to adopt new technologies and approaches when appropriate.
Fixed-term: The funds for this post are available until 14 April 2025 in the first instance.
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For informal enquiries please contact Dr Janet Deane at email@example.com .
Please quote reference SD30506 on your application and in any correspondence about this vacancy.
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