Research Associate (Fixed Term)
Identification of novel vulnerabilities in pleural mesothelioma
The Marciniak group based in the Cambridge Institute for Medical Research (CIMR), is seeking a postdoctoral fellow to drive innovation in the diagnosis and treatment of pleural mesothelioma. In collaboration with the Garnett Group in the Wellcome Trust Sanger Institute and the Rintoul Group in the CRUK Cambridge Cancer Centre, you will use multi-omics analysis including genomics, transcriptomics and genome-wide CRISPR screening and high-throughput drug screening to identify novel vulnerabilities in mesothelioma.
You should have a track record in wet-lab cancer biology and possess a PhD in a relevant discipline. Prior experience of bioinformatics analysis would be advantageous, but not essential as training will be provided.
The successful applicant will join a diverse team of basic and translational scientists and clinicians across the wider Cancer Research UK Cambridge Cancer Centre (Thoracic Cancer Programme). We are committed to promoting an exciting, rewarding and healthy working environment and strive to support the career goals of our team members.
Fixed-term: The funds for this post are available for 2 years in the first instance, with the possibility of extending to 3 years.
Recent relevant papers include: Marciniak SJ, Chambers JE, Ron D (2022). Pharmacological targeting of endoplasmic reticulum stress in disease. Nat Rev Drug Discov. 21: 115-140
Shamseddin M, Obacz J, Garnett MJ, Rintoul RC, Francies HE, Marciniak SJ (2021). The use of preclinical models for malignant pleural mesothelioma. Thorax 76(11):1154-1162
Obacz J, Yung H, Shamseddin M, Linnane E, Liu X, Azad AA, Rassl DM, Fairen-Jimenez D, Rintoul RC, Nikoli¿ MZ, Marciniak SJ. Biological basis for novel mesothelioma therapies. Br J Cancer. 2021 Oct;125(8):1039-1055.
Ye S, Azad AA, Chambers JE, Beckett AJ, Roach L, Moorcroft SCT, Aslam Z, Prior IA, Markham AF, Coletta LP, Marciniak SJ* and Evans S* (2020). Exploring high aspect ratio gold nanotubes
Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.
Please contact Professor Stefan Marciniak at sjm20@cam.ac.uk and Professor Robert Rintoul at rcr39@cam.ac.uk for further information.
Please quote reference SC30374 on your application and in any correspondence about this vacancy.
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