The ALBORADA Drug Discovery Institute (ADDI), part of the University of Cambridge CIMR Division of Translational Medicine (http://cambridge-ddi.alzheimersresearchuk.org/), is seeking an experienced biologist or biochemist with expertise in cellular and molecular biology techniques to join its established team. The ALBORADA DDI is part of a network of world-class Drug Discovery Institutes, funded by Alzheimer's Research UK, forming the Alzheimer's Research UK Drug Discovery Alliance. The work of the DDI at Cambridge is aimed at validating new drug targets and identifying potential new drugs for the treatment of Alzheimer's disease as well as other forms of neurodegeneration.
The successful candidate will join our team responsible for target validation, target engagement and cell-based assays and will use neuronal models to identify and validate novel targets and mechanisms of potential therapeutic value. The successful candidate will be a lab-based biologist who has obtained a PhD and has relevant experience from either academia or industry. We welcome applications who have just completed a PhD or those with additional, relevant post doctoral experience. They will be expected to provide scientific leadership, potentially supervise junior staff, be intellectually involved in a range of drug discovery and target validation projects as well as be responsible for developing novel and relevant assays for use by the biology team.
You will have significant experience in the manipulation and analysis of gene/protein function in mammalian cells as well as the use of a range of biochemical, molecular and cellular readouts. Experience with protein purification and working with disease relevant proteins that are prone to misfolding would be desirable. Experience in areas of neurodegenerative disease such as neuroinflammation or the cerebral vascular system would be an advantage.
Working with chemists and other biologists in a stimulating and collaborative environment with opportunities for training and development, the successful candidate will be expected to be organized, self-motivated, flexible when required, eager to identify and implement improvements to protocols and processes, and to be a team player. Time-management and record-keeping skills, and interpersonal and communication skills are also expected.
Specific enquiries about the post may be addressed to Dr. James Duce (email@example.com).
Fixed-term: The funds for this post are available until 31 October 2022 in the first instance.
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Closing Date: 18th October 2020.
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