Fixed-term: The funds for this post are available for 3 years in the first instance.
Project title: Antimicrobial Bioactive Composites with Controlled Resorbability Applications are invited for a Marie Sklodowska-Curie Early Stage Researcher to work with Professor Ruth Cameron and Professor Serena Best at the Cambridge Centre for Medical Materials in the Department of Materials Science and Metallurgy, University of Cambridge (https://www.ccmm.msm.cam.ac.uk/directory/faculty).
The project will involve:
- production and characterisation of micro- and nano-particles of bioactive substituted ceramics containing ions with bactericidal potential (e.g. Ag, Cu etc.)
- incorporation of these particles into resorbable polymers to form a composite
- development and optimisation of methods for particle dispersion in composites and evaluation of mechanical response and degradation behavior
- characterisation of the material properties of the composites using a range of different techniques
- an assessment of cell behaviour in contact with the materials
- a composition survey using preliminary tests for antimicrobial action The experiments will result in a series of compositions with varying degradation rates and mechanical properties controlled by the polymer composition and the filler content. The chemical nature of the filler particles will determine the bone bonding / bactericidal capacity of the composites. At the end of the project, it will be possible to rank the compositions according to their degradation rate, potential for bone repair.
The successful applicant will perform experiments to prepare the antimicrobial materials and structures, and the characterise these using techniques including X-ray microtomography, electron microscopy, X-ray diffraction, thermal analysis, FTIR and biological characterization.
The ESR will travel abroad for research secondments at partner organisations of the BIOREMIA Network (e.g. at Goeteborgs Universitet-Sweden, Ashland Specialities Ireland Ltd., Stryker Trauma GmbH -Germany) and will participate in specialised training meetings and international conferences.
Applicants must at the time of recruitment:
- 1) Be in the first 4 years (full-time equivalent) of their research careers
- 2) Have not resided in United Kingdom for more than 12 months in the last 3 years
- 3) Have not been awarded a doctoral degree.
Degree requirement: Applicants must hold a Master's degree or equivalent in Materials Science and Engineering or Physics providing access to PhD programs and should have experience with experimental research.
Applicants must have excellent proficiency in written and spoken English as indicated on the University website for graduate admissions https://www.graduate.study.cam.ac.uk/international/competence-english.
Applicants must have strong motivation and ability to collaborate in an interdisciplinary and international team This position is part of the European Training Network ''BIOREMIA'' dealing with research on novel biofilm-resistant materials for hard tissue implant applications. BIOREMIA offers the possibility to pursue the PhD within the Network at different universities and industrial companies from 10 European countries (Germany, Austria, Italy, Sweden, Greece, UK, Spain, Ireland, France, and Switzerland). The duration of the appointment is 3 years, starting Summer 2020, and the salary will comprise a living allowance circa 44,800.00 Euros per year plus allowances.
Background information on all ESR positions and BOREMIA Network is available at www.bioremia.eu BIOREMIA ("biofilm-Resistant Materials for hard tissue Implant Applications") is funded by the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska -Curie grant agreement no. 861046.
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Applicants should apply online, but any questions or queries should be submitted by email to Anna Perkins, firstname.lastname@example.org
The covering letter should make clear how the application meets the eligibility criteria for participation in a Marie Slodowska-Curie Innovation Training Network funded by the European Commission under Horizon 2020.
Please quote reference LJ22069 on your application and in any correspondence about this vacancy.
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