Fixed-term: The funds for this post are available for 12 months in the first instance.
The Wellcome Trust - Medical Research Council Stem Cell Institute draws together outstanding researchers from 25 stem cell laboratories in Cambridge to form a world-leading centre for stem cell biology and medicine. Scientists in the Institute collaborate to generate new knowledge and understanding of the biology of stem cells and provide the foundation for new medical treatments.
We are looking for a self-motivated, reliable and well-trained post-doctoral researcher to join our research team of Dr. Bon-Kyoung Koo. His team will investigate the role of E3 ubiquitin ligases (E3s) in regulating responsiveness of stem cells to instructive signals. The project will focus on intestinal stem cells. These stem cells are rapidly dividing adult stem cells, stemness of which is regulated by multiple signalling pathways. The main objective is to identify E3s that are involved in this process. Advanced mouse genetics, 3D organoid culture and diverse cellular and biochemical approaches will be combined to explore the role of E3s that are enriched in intestinal stem cells.
Requirement: A PhD degree. At least one publication with 1st authorship in a high impact journal. Strong background in biochemistry and molecular biology. Strong background in cell biology such as vesicle sorting, endocytosis, and ERAD pathway. Strong background in signalling pathway analysis and experience with genetic models. A proven capacity to design, execute and correctly interpret your own experiments. Good communication skills in English. Highly independent, motivated, ambitious, and collaborative person.
Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.
To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.
The closing date for all applications is the Monday 29th September 2014.
Please upload your current CV and Cover Letter with your application.
Informal enquiries are also welcome via email: firstname.lastname@example.org.
Interviews will be held in the middle of October 2014. If you have not been invited for interview by 10th October 2014, you have not been successful on this occasion.
Please quote reference PS04237 on your application and in any correspondence about this vacancy.
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