We are looking for a Post-doctoral Research Associate to join the group of Professor Allan Herbison focussed on understanding the neural networks that control puberty and fertility in mouse models. Studies will investigate the cellular mechanisms through which the two different hypothalamic populations of kisspeptin neurons control the activity of the gonadotropin-releasing hormone (GnRH) neurons. In particular, we are interested in understanding the ionic and synaptic mechanisms enabling these neuronal populations to exhibit and drive episodic activity. Brain slice studies are undertaken within the context of molecular-cellular-systems levels investigations in the laboratory using the latest neuroscience approaches. This is an exciting opportunity to join a newly formed research group recently relocated from the University of Otago, New Zealand, see https://www.pdn.cam.ac.uk/directory/allan-herbison.
You should have significant experience in acute brain slice patch-clamp electrophysiology, preferably from fluorescently-tagged neurons derived from genetic mouse models. Prior experience with the optogenetic manipulation of neurons, undertaking acute brain slice GCaMP calcium imaging, and working with hypothalamic circuitry would be an advantage.
Candidates should have a PhD (or about to be awarded a PhD) in neuroscience and a strong motivation to lead and undertake research at the forefront of hypothalamic neuroscience.
Fixed-term: The funds for this post are available until 1 September 2024 in the first instance.
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