The Cambridge Breast Cancer Research Unit (CBURU) is a purpose built research facility attached to the Cambridge Breast Unit at Addenbrookes Hospital, CUHT. It is involved in cutting edge clinical and laboratory research into breast cancer and is staffed by a multi-disciplinary team, including oncologists, pathologists, radiologists, nurses, research assistants and laboratory staff involved in translational research. The CBCRU is led by the Director, Professor Carlos Caldas and managed by a steering committee currently comprising the director, Deputy Director, other consultant oncologists and the CRUK Cambridge Centre Breast Cancer Programme Manager.
We are looking for an enthusiastic and independent research coordinator to work alongside existing CBCRU translational research staff to coordinate the PBCP project and other related translational studies. The PBCP is the Cambridge Cancer Centre's flagship Whole Genome sequencing (WGS) project, which aims to aims to offer whole genome sequencing to every eligible patient being treated at the Cambridge Breast Unit (CBU) within a clinically relevant timeframe. Information gained from sequencing data significantly enhances the clinical management of individual patients' disease, and the effectivity of their treatment plan.
The PBCP coordinator will run the PBCP under the guidance of the coordinating clinician, and facilitate the opening of the program at other regional and national centres. The role-holder will be required to create, maintain and amend all ethical and regulatory documentation throughout the lifetime of the project, and manage sample workflows, both internally and from other sites. The PBCP coordinator is expected to anticipate and identify potential barriers to the smooth-running of the project and troubleshoot/resolve any issues. This will include ensuring that all research activities are run according to good clinical practice (GCP) standards, and developing standard operating procedures (SOPs), appropriate governance, and risk management strategies.
The PBCP coordinator will act as the first point of contact for co-ordination, recruitment, administrative and other enquiries from patients, and internal and external stakeholders (including industry partners). A key responsibility of this role is ensuring timely delivery of results to clinicians and patients, which the PBCP coordinator will achieve by managing the Oncogenetic Review Board (ORB) MDT process, and coordinating the delivery of clinical and genomic results for decision-making at ORB/tumour board MDT. Following on from ORB/tumour board MDT meetings, the PBCP coordinator will be responsible for producing patient genomic results and returning this information to patients in an accurately worded, and appropriate, manner.
Central to the PBCP coordinator role is the requirement to maintain the quality, accuracy and timeliness of data management and ensure that the collection of study data is complete, accurate and up to date. As the PBCP study opens externally, the coordinator will be responsible for developing new methodologies to record and collate data for inclusion of partners from other national sites, for monitoring external data collection, and resolving discrepancies. Furthermore, the role-holder will be responsible for delivering internal reports/data for the project, and will be expected to actively participate in preparation of grant funding applications/reports or other forms of external support related to the project or associated translational work.
The PBCP coordinator role sits within the CBCRU Translational team, a group of highly trained and dedicated research professionals who support a number of translational breast cancer studies. The Translational team work closely together and provide cross-cover for tasks such as identifying, consenting and recruiting breast cancer patients suitable for translational research studies, reviewing MDT outcomes, clinic and theatre lists and liaising with staff and patients to organise patient appointments, results return and follow-ups. The PBCP coordinator will be responsible for line managing and supporting junior coordination staff within the Translational team, and will provide cross-cover support for other translational studies and clinical trials run through the CBCRU where required.
This is an exciting opportunity to join a ground-breaking oncogenomic study at a pivotal point in the study timeline, and would suit someone with a passion for facilitating translation of cutting-edge cancer research into a clinical setting. Full training will be given.
The PBCP project is led by Professor Carlos Caldas and Dr Jean Abraham, and this appointment will be line managed by Dr Jean Abraham.
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Fixed-term: The funds for this post are available until 28 March 2021 in the first instance.
Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment and a standard Disclosure and Barring Service check. This appointment also requires a Research Passport application.
Closing date for receipt of completed applications is 13 October 2019, with interviews expected to be held in mid-November 2019.
Informal enquiries may be made to Dr Anthea Messent, the CRUK Cambridge Centre Breast Cancer Programme Manager (email@example.com).
Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.
Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.
Please quote reference RD20630 on your application and in any correspondence about this vacancy.
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