University of Cambridge

Job Opportunities


Principal Research Associate in Functional and Translational Genomics (Fixed Term)

The Department of Public Health and Primary Care (DPHPC; head: Professor John Danesh) within the School of Clinical Medicine wishes to appoint a Principal Research Associate in Functional and Translational Genomics. The post-holder will be an independent academic scientist responsible to the Head of the DPHPC.

The Principal Research Associate in Functional and Translational Genomics will provide internationally recognised leadership in an emerging research area that is synergistic with major initiatives in genomic discovery science. The post-holder will exploit these data-rich initiatives to translate genetic association discoveries into molecular mechanisms and actionable clinical insights, thereby providing a rational basis for therapeutic target prioritisation.

The post-holder will have extensive experience in functional genomics, including experimental approaches (e.g. recall-by-genotype, genome engineering, cellular reprogramming) and bioinformatics approaches (e.g. genome annotation, statistical colocalization, phenome-scans). They will have the ability to link large-scale genetic epidemiology and systems genomics with molecular biology and clinical medicine.

The post-holder will be expected to have strong quantitative skills (e.g. experience in working with and manipulating large-scale genetic data) and experimental skills (e.g. various functional genomics and molecular biology techniques), as well as an appreciation and understanding of clinical medicine approaches in relation to cardiovascular disease.

The post-holder will be a senior academic in the Department and will be expected to develop an independent programme of research that is embedded in the unique research ecosystem provided by the Cambridge Biomedical Research and Wellcome Genome Campuses. The post-holder is also expected to collaborate with existing academic and industry partners but also initiate new collaborations.

The main responsibilities of the post-holder will include:

Establishment of a research programme in Integrative Genomics, synergistic with the overall objectives and strategies of the Department.

Contribution to the organisation, development, delivery and assessment of teaching in the various programmes run by the Department (see below).

The successful candidate will be based at the Department of Public Health and Primary Care, one of Europe's leading academic departments of population health sciences, comprising ~400 staff and graduate students, which has key strengths in genetic epidemiology, biostatistics, population cohorts and chronic disease. The candidate will also be jointly based at the Department of Human Genetics at the Wellcome Sanger Institute, the UK's premier centre for genomic discovery, with access to state-of-the-art facilities and resources.

This position is full-time. Funding is available for 3 years in the first instance from commencement in post.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Please ensure that you upload a covering letter, CV and list of publications in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

The closing date for applications is 24 July 2019.

There will be a departmental interview which will be held week commencing 5 August 2019. Followed by a formal interview with the Faculty of Clinical Medicine Selection Committee which will take place at a later date.

If you have any questions about this vacancy or the application process, please contact Professor John Danesh,

Please quote reference RH19202 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Further information

Apply online