University of Cambridge

Job Opportunities


Research Associate (Fixed Term)

A Postdoctoral Research Associate position is available within Dr Giles Yeo's group at the Institute of Metabolic Science (IMS). Supported by the Medical Research Council, this post will involve the molecular characterization in human neurons of genes associated with severe obesity identified from consanguineous pedigrees.

Scientists with a strong background in molecular and cell biology are encouraged to apply. An aptitude for and interest in developing more bioinformatic expertise, particularly in the area of analysing single cell RNA sequencing data, would be advantageous. An understanding of mammalian neurobiology would be very helpful as genes associated with severe obesity are likely to function largely within the brain. The role holder will work closely with other members of the group on this research programme, in addition to developing their own independent research ideas and questions.

You will be expected to:

  • To run a program of research investigating the molecular and cellular impact in human neurons of mutations in genes associated with severe obesity
  • Present research work and data within the Institute, nationally and internationally and to prepare and submit research for publication in peer-reviewed journals
  • Assist in providing instruction to graduate students and other members of the research group in the standard molecular biology/biochemistry techniques and cellular imaging techniques
  • Assist the Principal Investigator in preparation of manuscripts and proposals/applications to funding bodies

To be considered for this position, you must have:

  • A Ph.D. (or equivalent research doctorate) in cell biology or biochemistry, or a related discipline
  • Research experience in a broad range of molecular and cell biology techniques such as recombinant DNA techniques, Western blotting, immunostaining, and microscopy
  • Extensive experience with maintaining cells in culture, and techniques for genome editing and/or siRNA and plasmid DNA delivery
  • A degree of understanding of mammalian neurobiology
  • Presentation skills backed up by a record of national and/or international presentations
  • Communication skills including ability to work effectively within a team
  • The ability to impart knowledge and skills to graduate students and other members of the research team including graduate students
  • The ability to troubleshoot experiments and for the development of novel research tools and platforms
  • The ability to manage own workload in an organised way
  • Organisational skills including ability to organize and participate in collaborative research initiatives and projects
  • The ability to prepare and analyse data for publication in scientific journals and to present scientific data to peers in seminars and at conferences

Informal enquiries can be made to Dr Giles Yeo, Metabolic Research Laboratories, Level 4, Wellcome Trust-MRC Institute of Metabolic Science, Box 289 Addenbrooke's Hospital, Cambridge CB2 0QQ. Email:

Fixed-term: The funds for this post are available until 30 June 2022 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment. This appointment also requires a Research Passport application.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

The closing date is 20 June 2019, with interviews to be confirmed.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

Please quote reference RG19167 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Further information

Apply online