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Research Associate


Repositioning G-quadruplex-binding agents as antimalarial drugs

A postdoctoral research position is available in the laboratory of Dr Catherine Merrick, investigating the molecular mechanisms by which G-quadruplex binding agents can kill malaria parasites and the feasibility of repositioning such agents as candidate antimalarial drugs. G-quadruplex nucleic acid structures in Plasmodium are a major focus of research in the Merrick lab and this project will build on the recent publication by Harris et al., AAC 2018: 'G-quadruplex DNA motifs in the malaria parasite Plasmodium falciparum and their potential as novel antimalarial drug targets.' The project will involve a range of cutting-edge techniques in molecular genetics, genomics and cell biology across several Plasmodium species.

Applicants should hold a PhD in parasitology, molecular biology or genomics, with skills in cell culture, molecular biology and genomics/bioinformatics. Specific experience of Plasmodium culture, Plasmodium molecular genetics and genomic/transcriptomic techniques is desirable. The appointee will benefit from excellent facilities, including recently-refurbished Category-3 containment laboratories, and diverse expertise at the Cambridge Pathology Department.

The post will be available from Sept 1st 2019 Closing date for applications: 31st May 2019 Interviews will be held in mid June 2019

For further information please contact: cjm48@cam.ac.uk https://www.path.cam.ac.uk/directory/catherine-merrick/

Limited funding: The funds for this post are available for 2 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

Applications are welcome from internal candidates who would like to apply for the role on the basis of a secondment from their current role in the University.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Any enquiries relating to the application process please contact Jodi Smith - hr@path.cam.ac.uk

Please quote reference PK18984 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Further information

Apply online