The Hannon laboratory at the CRUK, Cambridge Institute is looking to recruit up to two talented and dedicated Senior Bioinformatician(s), to join its team and contribute to its cutting-edge research in the field of cancer biology.
The Hannon group has a long history of relevant and seminal work in the fields of molecular biology, cancer biology and technology development. This included the elucidation of key components of small RNA pathways, the development of shRNA knock-down and genome-wide library for genetic screening, exome-capture sequence enrichment, as well as the discovery of vascular mimicry as a driver of metastasis in a model of breast cancer. Recently, we are focusing on breast cancer using state of the art -omics technologies to investigate the progression of tumours, focusing in particular on the interactions between disease and the surrounding host tissue. Such interactions are incredibly complex and highly local, and therefore require novel methods, including in-situ and single-cell genetic measurements, to be appropriately studied.
Although they would participate to the research activities of the laboratory as a whole, the individual(s) will be expected to contribute their own innovative ideas resulting in potential new research directions within the global scope of the laboratory, the role holder(s) would work in the context of two main projects - details of which can be found in the further particulars document below.
The successful candidate(s) should have a strong background in bioinformatics, statistics and mathematical modelling, and prior experience working with both single-cell and bulk genomic and transcriptomic data. Excellent computer skills (programming, linux shell, sequencing analysis software) are essential. Prior experience with single-cell data analysis packages is a plus. A PhD in a relevant discipline (biology, mathematics, statistics or similar) is desirable but not essential. Some amount of wet lab experience (in particular in cell or molecular biology) is also desirable.
Candidates are expected to be good communicators, creative thinkers, and to be able to find novel solutions to problems and to take a leading position in furthering their areas of the project. Ability to collaborate effectively with people with different backgrounds in a multi-disciplinary environment is also highly valued.
For up to date information about the other projects in the Hannon research group, including our most recent publications, please see our website at: http://www.hannonlab.org/research/.
Fixed-term: The funds for this post are available for 3 years in the first instance.
Once an offer of employment has been accepted, the successful candidate will be required to undergo a security check.
To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.
The closing date is 11 March 2019, with the interview date TBC.
Please send applications in the following format: a CV; the names and contact details of two referees, one of which must be your most recent line manager; a cover letter explaining why you wish to be considered for this particular role, what you will bring to the project and listing your research experience to date.
Please quote reference SW18134 on your application and in any correspondence about this vacancy.
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