The Rosenfeld lab at the Cancer Research UK Cambridge Institute, University of Cambridge, pioneers new approaches for noninvasive molecular diagnostics and analysis of cancer genomes and evolution, using next-generation sequencing of circulating cell-free tumour DNA (ctDNA). We work with large collections of patient material from different clinical studies, which we analyse by both genome-wide methods and targeted methods for sensitive mutation detection. We aim to develop novel tools for cancer diagnostics by developing improved methods and demonstrating clinical utility. Furthermore, we explore the biophysical properties of ctDNA with the aim of identifying its origins and interactions.
The lab routinely uses amplicon, shallow and deep whole-genome sequencing, and custom capture methods to profile samples from different bodily fluids from patients with various cancer types. The group is a dynamic mix of molecular biologists, bioinformaticians and clinical fellows providing a unique environment for development in cancer genomics, with a strong focus on clinical application. The successful candidate will work closely with the other bioinformaticians in the group to develop and maintain databases and streamline analysis pipelines to ensure timely delivery of results. They will also support non-computational members of the group in devising and implementing project specific analyses.
We are seeking to recruit an outstanding scientist who will have responsibilities over data management, software development and deployment. The ideal applicant will have an MSc/PhD and significant or extensive experience in data management, bioinformatics or computational biology, genome research, or closely related fields. You will be a highly motivated individual with excellent communication skills and who is extremely organised. You will be able to work independently and interact well in a multi-disciplinary team environment.
Informal enquiries may be made to the Rosenfeld lab management team; firstname.lastname@example.org.
Fixed-term: The funds for this post are available for 3 years in the first instance.
Once an offer of employment has been accepted, the successful candidate will be required to undergo a security check.
To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.
The closing date is 6 March 2019, with the interview date TBC.
Please ensure that you upload a covering letter and CV in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.
Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.
Please quote reference SW18091 on your application and in any correspondence about this vacancy.
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