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PhD studentship (Fixed Term)


Characterising animal IFIT proteins; universal inhibitors of viral protein synthesis?

A PhD studentship co-funded by the Department of Pathology, University of Cambridge and The Pirbright Institute is available to work on a collaborative project in the laboratories of Dr Trevor Sweeney and Dr Dalan Bailey. This exciting project will investigate the role of interferon stimulated genes in regulating viral pathogens of animals. The position is available from October 2019 or as soon thereafter as the suitable candidate can start.

Informal enquires may be made to Dr Trevor Sweeney (ts629@cam.ac.uk) or Dr Dalan Bailey (dalan.bailey@pirbright.ac.uk).

Interviews will be held the week commencing 11th March 2019.

Project description The interferon-induced proteins with tetratricopeptide repeats (IFITs) are a family of antiviral proteins conserved throughout all vertebrates. IFITs are cytosolic proteins, upregulated upon infection, which play a key role in combatting viral infection. In this project a detailed analysis of IFIT complex assembly and their function in various animal species will be performed. Understanding the mechanistic basis and regulation of host innate immune activities may provide new routes to protecting animal health and improve our understanding of viral pathogenesis. The candidate will be trained in molecular virology techniques and analysis of host-pathogen interactions and will be encouraged to take an active part in all aspects of research from performing experiments to giving seminars and drafting research papers for peer review and publication.

Applicants should hold or be about to achieve a First or Upper-Second (2.i) class degree in a relevant subject. Additionally, the Department requires that by the time of interview all potential students must have fulfilled the language requirements for admission.

Full details of the projects and how to apply are available from the following link: http://www.path.cam.ac.uk/graduate/fully-funded-studentships

The studentships are available to UK nationals and EU students who meet the UK residency requirements. Further information about your fee status can be found at the following website: http://www.graduate.study.cam.ac.uk/finance/fees/what-my-fee-status.

Applications from ineligible candidates will not be considered.

Fixed-term: The funds for this post are available for 3 years in the first instance.

The closing date for applications is 28/02/2019. Interviews will be held the week commencing 11th March 2019.

General queries regarding these positions should be directed to graduate.studies@path.cam.ac.uk or Izzy Starkey 01223 333872.

Please quote reference PK18078 on your application and in any correspondence about this vacancy.

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