We invite applications for a post-doctoral researcher to join the plant-parasite interactions group (Dr Sebastian Eves-van den Akker) at the University of Cambridge Department of Plant Sciences. Funding is available for a full time position for one year in the first instance, with a flexible start date from March 2019 for the following 3 months.
The research will be part of an ambitious Isaac Newton Trust/Wellcome Trust/University of Cambridge joint research grant to develop CRISPR-mediated proof-of-principle genetic modification of plant-parasitic nematodes. The successful applicant will use available genomic resources to design constructs to induce specific modifications in plant-parasitic nematode genes that produced measurable phenotypes in other nematode species. They will deliver RNA-protein complexes to parasitic nematodes by micro-injection, and measure the success of genome editing events using a combination of phenotypic screening, flow-cytometry, and/or whole genome re-sequencing.
The successful applicant will work closely with the rest of the team to develop and trouble-shoot ideas, and will participate in the dissemination of research through publications and oral presentations both within the department and the transformation of plant-parasitic nematodes consortium.
Applicants should possess, or will soon be completing, a PhD in an appropriate area. It is essential that applicants: 1) have expertise in micro-injection of nematodes (model and/or non-model species), 2) have experience in the design and execution of experiments using CRISPR, and 3) are persistent, inventive, have exceptional problem-solving abilities. Previous experience of working with plant-parasitic nematodes and maintaining plants in sterile tissue culture/plant care in a scientific environment is not required - training will be provided. Good interpersonal skills and enthusiasm are necessary.
Fixed-term: The funds for this post are available for 1 years in the first instance.
To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.
Please upload a CV and covering letter describing how you meet the post specifications. Contact Dr Eves-van den Akker (email@example.com) if you have any queries. If you do not receive a response from us one month after the closing date you should consider that your application has not been successful this time.
Please quote reference PD18011 on your application and in any correspondence about this vacancy.
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