A position for a research assistant has arisen in the lab of Professor Gerard Evan, University of Cambridge, Department of Biochemistry, Cambridge (http://www.bioc.cam.ac.uk/uto/evan) to further our ongoing studies on the development and maintenance of pancreatic cancer. The research seeks to determine whether pancreatic cancer is driven and maintained by the activation of common and obligate regenerative programmes in the pancreatic epithelium and its attendant stroma elicited by oncogenic mutations. Our work suggests that deregulated expression of the Myc protein, a highly pleiotropic "master" switch, modulates a wide variety of mechanistically diverse processes. We have established models in which expression and/or activity of Myc can be rapidly and reversibly switched in the pancreas and we now seek a research assistant to continue our studies investigating the possibility that inhibition of Mys specific downstream targets elicits tumour regression.
Applicants should have a BSc or equivalent. A background in tumour biology and previous experience in molecular and cellular biology and in mouse models of tumourigenesis is desirable.
Fixed-term: The funds for this post are available for 10 months in the first instance with possibility of extending.
This appointment is subject to a security check. Whether an outcome is satisfactory will be determined by the University.
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Please quote reference PH16095 on your application and in any correspondence about this vacancy.
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