We have a position available in the laboratory of Dr Yorgo Modis in the Department of Medicine at the University of Cambridge to study cell entry and innate immune recognition of enveloped RNA viruses. This post is funded by the Wellcome Trust.
We seek an individual to contribute on multiple ongoing research projects on the mechanisms of cell entry and innate immune recognition of enveloped RNA viruses using a combination of biochemical, biophysical and cell biological approaches.
Candidates must have a BA, BSc, MA or MSc (or equivalent) in the biological or biomedical sciences, and relevant research experience in eukaryotic cell culture, protein purification, and molecular biology.
The overarching goal of the Modis lab's research program is to gain a mechanistic understanding at the molecular level of how important pathogens interact with their host cells during infection. We seek to understand: How do enveloped RNA viruses deliver their genome into the cytosol? How are innate immune responses to viral RNA generated, amplified and regulated? How does the cell regulate transcription of integrated viral sequences? We employ a complementary set of approaches including X-ray crystallography, electron microscopy, solution biophysics, fluorescence microscopy and cell biological approaches to understand the molecular mechanism of these processes in molecular-level detail. Our projects have important potential applications in global health.
The Modis Laboratory is part of the new Molecular Immunity Unit within the Laboratory of Molecular Biology (LMB). It benefits from the unique scientific environment and infrastructure of the MRC-LMB, and from direct links to the Infectious Disease and Immunology community within the Department of Medicine (www.mrc-lmb.cam.ac.uk/ymodis/).
Informal enquiries are welcomed, and should be directed to Dr. Modis at email@example.com
Fixed-term: The funds for this post are available until 31 March 2019 in the first instance.
Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.
To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.
Please ensure that you upload a covering letter and CV in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.
Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.
Closing Date: 3rd July 2018
Interview Date: To be confirmed
Please quote reference RC15782 on your application and in any correspondence about this vacancy.
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