The Alzheimer's Research UK Cambridge Drug Discovery Institute (DDI), part of the University of Cambridge CIMR Division of Translational Medicine (http://cambridge-ddi.alzheimersresearchuk.org/), is seeking a biologists or biochemists with expertise in cellular and molecular biology techniques to join its growing team. The Cambridge DDI is part of a network of world-class Drug Discovery Institutes, funded by Alzheimer's Research UK, forming the Alzheimer's Research UK Drug Discovery Alliance. The Cambridge DDI will prosecute drug discovery projects from target to in vivo proof of concept and beyond for novel targets in the neurodegeneration therapeutic area.
The successful candidates will join our team responsible for target validation, target engagement and cell-based assays and will develop and execute a range of experiments in neuronal models to identify and validate novel targets and mechanisms of potential therapeutic value. The successful candidates will be a lab based biologist who has either obtained a PhD (or equivalent) or is close to completion and with relevant experience from either academia or industry. They will be expected to provide scientific leadership, potentially supervision of junior staff and be intellectually involved in a range of drug discovery and target validation projects.
You will have experience in the manipulation and analysis of gene/protein function in mammalian cells, including gene transfer/RNAi (experience of CRISPR/Cas9 technology is desirable), analysis of protein-protein interactions, gene expression and gene functional analysis in neuronal models. Experience with imaging-based assays and/or FACS-based screening would be desirable. Experience of drug discovery and a relevant area of neurodegenerative disease would be an advantage. Working with chemists and other biologists in a stimulating and collaborative environment with opportunities for training and development, the successful candidates will be expected to be organized, self-motivated, flexible when required, eager to identify and implement improvements to protocols and processes, and to be a team player. Time-management and record-keeping skills, interpersonal and communication skills are also expected.
Specific enquiries about the post may be addressed to Dr. James Duce (firstname.lastname@example.org).
Fixed-term: The funds for this post are available until 31 August 2020 in the first instance.
To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.
Please ensure that you upload a covering letter and CV in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.
Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.
Closing date for applications is the 21st May 2018, with interviews yet to be confirmed by the department.
Please quote reference SA15379 on your application and in any correspondence about this vacancy.
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