The Cancer Research UK Cambridge Institute (CRUK CI), a department of the University of Cambridge, hosts research ranging from basic cancer and computational biology through to translational research and clinical application. To find further details about the Institute, please go to www.cruk.cam.ac.uk
The Institute supports a dynamic and highly successful academic programme composed predominantly of PhD students and Clinical Research Training Fellows (CRTFs) who contribute to the on-going success of our research teams. The involvement of CRTFs brings the added benefit of 'bridging' between our research in the laboratory and the clinical activities in the nearby Addenbrooke's Hospital.
Through our commitment to this training programme, we aim to ensure a future generation of outstanding translational research leaders. Consequently, we seek applications for the CRTF role from clinicians who have the potential to pursue a career as an academic clinician.
Professor Kevin Brindle offers an excellent opportunity for an individual wishing to gain experience in novel cancer imaging methods. The Brindle laboratory have been developing a novel MRI method for imaging tumour metabolism using hyperpolarized 13C-labelled cell metabolites, which they have been using to detect disease and disease progression and monitor response to treatment. In glioblastoma this has involved studies in patients and in patient-derived xenograft (PDX) models. They are now seeking to extend these studies to include high resolution mass spectrometric imaging, where we will infuse patients and PDX models immediately prior to surgery with 13C-glucose and then conduct mass spectrometric imaging of the labelled glucose and its metabolites in freshly excised tumour tissue. This project, which is part of the CRUK Grand Challenge Award: "Building a 'Google Earth' of cancer", promises new insights into tumour metabolism in vivo.
The successful individual will have a prominent role in the recruitment of patients with glioblastoma, and will collaborate with the attending surgeon in administering 13C-labelled substrates immediately prior to surgery and in collecting freshly excised tumour tissue for mass spectrometric imaging.
The post will be held in the CRUK Cambridge Institute, under the direction of Professor Kevin Brindle (Senior Group Leader and Professor of Biomedical Magnetic Resonance).
Professor Brindle seeks to recruit a clinician who has either completed or is close to completing their specialist training in neurosurgery, clinical oncology or radiology. However, other clinically trained individuals, at an earlier stage of their career would also be considered.
Fixed term: The funds for this post are available for 3 years in the first instance.
A Clinical Research Training Fellowship (CRTF) funds clinicians for three years to undertake Out of Programme research leading to the award of a PhD. The funding includes a clinical salary and University Composition Fees. The successful candidate must be accepted by the University of Cambridge for graduate study. This appointment requires an Honorary Clinical Contract.
How to apply:
Please email Professor Kevin Brindle (firstname.lastname@example.org) with the following:
-Your academic CV (which should include details of any prior research experience)
-Your statement of interest
-The names and contact details of 2 academic referees
The closing date for applications is Saturday 31st March 2018.
Please quote reference SW14911 on your application and in any correspondence about this vacancy.
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