University of Cambridge

Job Opportunities


Research Associate (Fixed Term)

University of Cambridge Department of Veterinary Medicine Stevenage Bioscience Catalyst Site

Limit of Tenure one year in the first instance

A postdoctoral research associate position is available at the Stevenage Bioscience Catalyst site, associated with Professor Clare Bryant and David Klenerman. This project aims to characterise and develop our novel small molecule inhibitors of Toll-Like Receptor 4 as potential therapeutics against Alzheimer's Disease. The postholder will use established HEK293 reporter gene assays and THP-1 macrophage ELISAs to measure the antagonistic activities of small molecules and to investigate their modes of action. Alongside this, the successful applicant will develop assays to examine TLR4 inhibition in astrocyte and microglia cell lines, in collaboration with the Department of Chemistry.

Applicants must hold a PhD in pharmacology, biochemistry, molecular biology, immunology or a related discipline. Useful experience would include handling the cell lines mentioned previously, working with neural cell lines and knowledge of innate immunology.

If you have any questions regarding this vacancy, please contact Doctor Joe Boyle by email on or Professor Clare Bryant by e-mail on

Fixed-Term: This project is currently funded for one year in the first instance, with a second year of funding dependent on completion of specific milestones.

Closing date 7 February 2018

Interviews will be held: 9 March 2018

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

To apply online for this vacancy and to view further information about the role, please visit: This will take you to the role on the University's Job Opportunities pages. There you will need to click on the 'Apply online' button and register an account with the University's Web Recruitment System (if you have not already) and log in before completing the online application form.

Please quote reference PP14447 on your application and in any correspondence about this vacancy.

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Further information

Apply online