University of Cambridge

Job Opportunities


Clinical Research Associate (Fixed Term)

Applications are invited for a one year fixed term Clinical Research Associate position based in the Department of Medicine in Professor Ken Smith's laboratory (

The Smith Laboratory has recently demonstrated that genetic variants associated with disease outcome are distinct from those driving disease susceptibility, and that common mechanisms, including T cell exhaustion, drive disease prognosis across a range of immune-mediated diseases. Work in the laboratory, combining human and model organism and state-of-the-art bioinformatic methodology, is currently focussed on gaining further insight into these pathways and how they may be targeted therapeutically to directly benefit patients. Example publications include McKinney et al Nature Med 16:586-591,2010; Lyons et al New Engl J Med 367:214-223,2012; Lee et al Cell 155:57-69,2013 and McKinney et al Nature 2015.

This post will involve the collection and collation of clinical data from well-characterised patient cohorts spanning a number of immune and inflammatory diseases, in particular systemic lupus erythematosus, vasculitis and inflammatory bowel disease. Clinical duties will be with the Vasculitis and SLE Service (Dr David Jayne).

Applicants should be medically qualified, have, or be eligible for, full GMC registration, and be training (or trained) in Nephrology.

Fixed-term: The funds for this post are available for 1 years in the first instance.

This appointment requires an Honorary Clinical Contract.

Informal enquiries may be directed to Professor Ken Smith (

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Closing date: 30th January 2018

Please ensure that you upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including e-mail address and phone number, one of which must be your most recent line manager.

Please quote reference RC14391 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Further information

Apply online