We are looking for two Research Associates to join the laboratory of Professor Ian Goodfellow, based on the Cambridge Biomedical Campus within Addenbrooke's Hospital, starting from February/March 2018. The positions are part of a large programme of work funded by the Wellcome Trust to study norovirus-host interactions and builds on a recent development of an organoid culture system to study human norovirus biology. The post holder will join a diverse and dynamic group of researchers based in the Division of Virology, Department of Pathology, based at Addenbrooke's hospital, Cambridge (www.calicivirus.co.uk).
Post one will focus primarily on the dissection of the role of lipid homeostasis pathways in viral replication using norovirus replicons, murine norovirus and human norovirus organoid infections.
The second post will focus on the characterisation of norovirus entry mechanisms, with the overarching aim of identifying molecules involved in human norovirus entry and genome release.
The candidate should have the following skills: Essential: - Proven track record in molecular virology and/or cell biology - Proven ability to work to delivery research at an internationally competitive level
Desirable: - Experience in the use of organiod technology - Experience in viral reverse genetics - Experience with CRISPR/CAS9 gene editing - Experience with proteomics
Candidates should hold a PhD, or equivalent qualification.
In most cases, it is expect that the candidate have been awarded their PhD but where the successful applicant does not yet have a PhD, he/she will normally be under-appointed as a Research Assistant in a Research Associate post (on the understanding that he/she will be appointed as a Research Associate upon successful completion of his/her PhD). The higher Research Associate salary should be backdated to the submission date of their thesis or start date whichever is the later.
The post-holders should be highly motivated, and have the ability to plan and conduct high quality experimental work within a multidisciplinary team. The ability to work both as part of a team, and independently, coupled with excellent communication, organizational and problem solving skills are required. The duties/responsibilities of these posts include developing and driving research objectives, writing up work for presentation and publication, assisting in the supervision of student research projects, and delivering seminars and occasional lectures as outlined on the Further Information Documents.
Fixed-term: The funds for this post are available from March 2018 until 30 September 2022 in the first instance.
Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.
To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.
The closing date for applications is 31 January 2018 and interviews will be held during the week of the 19th of February. General queries should be directed to firstname.lastname@example.org or 01223 333940.
Please quote reference PK14246 on your application and in any correspondence about this vacancy.
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