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Job Opportunities


CMDL Senior Bioinformatician (Fixed Term)

Applications are invited for a full-time position of a Senior Bioinformatician to take on a strategic role in the expansion and future developments of bioinformatics within the Cancer Molecular Diagnostic Laboratory (CMDL).

Following on the successful major centre funding award from Cancer Research UK this is an exciting time to join the CRUK Cambridge Centre (CRUKCC). The Integrative Cancer Medicine Programme is established and brings together knowledge, expertise and emerging technologies to establish a personalized, precision cancer medicine strategy that diagnoses cancer early and individually stratifies, treats and monitors all patients (

The CMDL is a key strategic resource for the Integrative Cancer Medicine (ICM) Programme aimed to translate cutting edge genomic methods for advanced diagnosis and clinical management of cancer supported by the CRUK Cambridge Centre and the NIHR-BRC ( This resource is one of the major resources in the ICM programme that also includes imaging, tissue resources, data integration, and clinical science. The genomic data and analysis is an integral and critical component of the ICM programme.

We are seeking a bioinformatician with an interest in molecular oncology, a flexible approach to work when required and the ability to help establish and lead a team of bioinformaticians. Experience of configuring and using Linux-based computational clusters, database design and maintenance, a good understanding of the principles of DNA sequencing analysis including NGS, and proficiency in using command-line and writing and running scripts are essential.

Embedded within the diverse and dynamic bioinformatics community at CRUK Cambridge Centre, the successful applicant will work directly alongside bioinformaticians from the Personalised Breast Cancer Project and other ICM clinical and translational initiatives to develop, implement and validate automated tools for the processing and analysis of High throughput sequencing data, associated with the development of comprehensive tumour profiling platforms. This work will align with ICM clinical programmes currently being developed in renal, kidney, and pancreatic cancer. The role will involve working closely with scientific staff in the evaluation of bioinformatics tools to assist in the analysis and interpretation of molecular aberrations and providing basic bioinformatics training and support for scientific staff within the Department. The ability to work well within a team and act as an efficient and pro-active service provider with good communication and presentation skills is essential.

The successful applicant will hold an MSc/PhD (or equivalent) in a relevant subject or have equivalent experience, and will hold a post-graduate qualification in Bioinformatics, System Biology, Computer Science, Math, Statistics or obtained equivalent knowledge through relevant and substantial experience. Significant programming and algorithm development experience is desirable. Data manipulation in a bioinformatics environment (e.g. Bioconductor, R, etc.) and experience with NGS data manipulation is essentials. Prior experience in molecular diagnostics or cancer genomics would be advantageous.

Fixed-term: The funds for this post are available until 31 March 2019 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a security check. This appointment also requires a Research Passport application.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

Closing date for applications is the 23rd November 2017, with interview dates yet to be confirmed by the department.

Please quote reference RD13764 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Further information

Apply online