University of Cambridge

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Research Associate in Structural Biology

Research Associate in Structural Biology: Structural basis of meiotic chromosome organization by the synaptonemal complex.

A postdoctoral position is available in the group of Prof. Luca Pellegrini in the Department of Biochemistry of the University of Cambridge, to work on the role of the synaptonemal complex in establishing the functional architecture of homologous chromosomes in meiosis, which is essential for correct chromosome pairing and genetic recombination (Syrjanen et al, eLife, 2017; Syrjanen et al, eLife, 2014). A multi-disciplinary approach involving biochemical and biophysical experiments will be used to elucidate the molecular mechanisms of synaptonemal complex assembly on the meiotic chromosome axis. The ultimate goal of the project is to achieve the biochemical reconstitution and structural analysis of meiotic chromosome organisation from purified protein components.

Successful candidates will hold or about to be awarded a PhD in Biochemistry, Biophysics or Molecular Biology and must be able to demonstrate a proven track record in conducting internationally-competitive research. Most of all, they must be exceptionally enthusiastic and motivated to succeed in fundamental research.

Applicants should submit a CV with list of relevant publications, a cover letter explaining why they are suitable for the position and contact information for at least two referees.

The position is available from January 1st, 2018 and is tenable for a period of one year initially.

Informal enquiries can be made to Luca Pellegrini at

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

If you have any questions about the application process, please contact Adriana Dote (

Please quote reference PH13585 on your application and in any correspondence about this vacancy.

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Further information

Apply online