The state-of-the-art Cancer Research UK Cambridge Institute is a joint venture between Cancer Research UK and the University of Cambridge, researching basic cancer and computational biology through to translational research and clinical application. Graduate students play a pivotal role in the continuing success of our research programmes and the Institute affords an excellent opportunity to start a research career in an environment committed to training outstanding cancer research scientists of the future.
Professor Sir Shankar Balasubramanian (SB) is seeking a student to work on the Epigenetic Features of the Genome. This position will be primarily based in the Balasubramanian lab in the CRUK Cambridge Institute.
Project details - The lab exploits both chemistry and biology to address fundamental mechanisms of genome function (http://www-balasubramanian.ch.cam.ac.uk). While many genetic determinants of cancer are known, alternative nucleic acid secondary structures and chemically modified DNA (or RNA) bases can be epigenetic features of nucleic acids that are important to normal biology and in oncogenesis. The project will explore chemical modifications as epigenetic features and how these influence secondary structure formation and function in the genome of normal and cancer cells.
Preferred skills/knowledge - The student will be highly motivated, capable of independent thought and have excellent communication skills with the ability to work collaboratively. Ideally, the candidate will have a strong background in molecular biology and/or biochemistry. A good knowledge of genomics and the chemistry/chemical biology of nucleic acids is highly desirable.
Funding - This studentship is funded by Cancer Research UK and includes full funding for University and College fees and in addition, a stipend of £19,000 per annum, initially for 3 years, with funding for a further year possible as required.
Eligibility - No nationality restrictions apply to this Cancer Research UK funded studentship. Applications are invited from recent graduates or final year undergraduates who hold or expect to gain a first/upper second class degree (or equivalent) in a relevant subject from any recognised university worldwide.
How to apply - Please follow the instructions on the following webpage: (http://www.graduate.study.cam.ac.uk/courses/directory/cvcrpdmsc/apply)
Notes on completing the application form - Course start date: 01 October 2018.
Completing the 'Research section' - In the 'Research Title' textbox, if you are only applying for consideration by one supervisor, insert their project title. If you wish your application to be considered by more than one, insert 'Cancer research'.
If you are applying for consideration by more than one supervisor, in the 'Research Summary' textbox, please insert the project title(s) being offered by the Supervisor(s) you wish to consider your application. Also in the 'Research Supervisor' textbox please insert the initials of the Supervisor(s) you wish to consider your application. Please also describe your research experience in the appropriate textbox.
Completing the 'Finance' section - We know that you are applying for a Cancer Research UK Studentship. If you have not already applied for other source(s) of funding, please tick 'no'. Then please tick 'yes' to be considered for Cambridge scholarships, and you will be considered for these in addition to a Cancer Research UK Studentship. You are not eligible for AHRC funding.
Course Specific Questions - Please add a Covering Letter as the last two pages of your CV. Your Covering Letter should explain why you wish to be considered for the studentship and describe the qualities and experience you would bring to the role. You will be asked to upload your CV (under Course Specific Questions).
Please quote reference SW13438 on your application and in any correspondence about this vacancy.
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