University of Cambridge

Job Opportunities


Research Associate (Fixed Term)

Combining 3D single molecule/super-resolution imaging with 3D genome structure determination to study nuclear architecture

Applications are invited for a postdoctoral Research Associate to work on a collaborative Wellcome Trust-funded research project between the Departments of Biochemistry, Chemistry and the Stem Cell Institute in Cambridge, focused on understanding mammalian interphase genome structure in mouse ES cells.

The aim of the project is to develop a highly efficient approach to combine 3D single molecule/super-resolution imaging with 3D genome structure determination of the same single mouse embryonic stem cell (see Stevens et al., Nature, 2017, 544, 59-64). This will be used to study factors affecting chromosome/genome structure and how this changes during differentiation.

We are seeking a highly motivated researcher with a PhD (or who expects to obtain one shortly), and expertise in either single molecule/super resolution imaging, single cell experiments or computational biology, who would like to work as part of a highly interdisciplinary team of biologists, chemists and mathematicians. For further details please contact either: Brian Hendrich (, Dave Klenerman ( or Ernest Laue (

Fixed-term: This post is available for 12 months in the first instance, with a possibility of longer term funding.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Enquiries about the online application process can be sent to Adriana Dote (

Please quote reference PH12751 on your application and in any correspondence about this vacancy.

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Further information

Apply online