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Research Associate: Pharmacology of Multi-Target Ligands of G-Protein Coupled Receptors


Fixed-term: The funds for this post are available for 1 year in the first instance.

Applications are invited for a post-doctoral research associate to join the research group led by Dr Andreas Bender at the Centre for Molecular Science Informatics in the Department of Chemistry from 1 October 2017, or as soon as possible thereafter. The ERC-funded project will employ experimental approaches to support our research on modelling the biological effects of compound mixtures as well as multi-target ligands, which is the main focus of the project from the computational side. This part of the project will be conducted in close collaboration with the group of Dr Graham Ladds at the Department of Pharmacology, which houses the equipment necessary for assaying multi-target ligands and related analyses.

Applicants should have (or be about to obtain) a PhD in pharmacology, biological chemistry or a related field. Expertise in the areas of G protein-coupled receptor pharmacology, mammalian tissue culture, knowledge of second messenger and protein kinase assays (e.g. cAMP, Ca2+ mobilisation, pERK1/2 etc.), experience of molecular biology (site direct mutagenesis and how this can be used for GPCRs), and knowledge of yeast-based systems for drug screening as applied to GPCRs are essential for the post. Previous successful experience in leading projects and working in interdisciplinary teams would be advantageous.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that you upload your Curriculum Vitae (CV), a covering letter and publications list in the upload section of the online application. If you upload any additional documents that have not been requested, we will not be able to consider these as part of your application.

For queries regarding the post, please contact Dr Andreas Bender (email: ab454@cam.ac.uk).

Please quote reference MA12652 on your application and in any correspondence about this vacancy.

The Department holds an Athena SWAN silver award for women in Science, Technology, Engineering, Mathematics, and Medicine.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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