University of Cambridge

Job Opportunities


Research Assistant in Molecular Biology, Wellcome Trust-MRC Institute of Metabolic Science (Fixed Term)

Applications are invited for a Research Assistant position to join a team led by Dr. Robert Semple where you will be responsible for supporting a study examining the potential utility of antibodies as a therapeutic intervention for human insulin resistance syndromes caused by genetic defects in insulin receptors. The post-holder's work may include, but will not necessarily be limited to, mammalian cell culture, Western blotting, assessment of post-translational modifications and signalling cascades downstream of the insulin receptor, and the application of standard molecular biology techniques (cloning, DNA/RNA extraction, genotyping).

Applicants should have a BSc, or equivalent degree, in Biochemistry or a related discipline. Experience in mammalian cell culture is absolutely essential, as is excellent organisational, record keeping skills and technical knowledge. Handling and use of antibodies, Western blotting, DNA extraction and genotyping is a requirement. More general experience with wider protein chemistry techniques, immunohistochemistry, and microscopy will be an advantage. You will also be enthusiastic, have good communication and team-working skills, and the ability to work independently when required.

Proposed start date: as soon as possible

Fixed-term: The funds for this post are available for 24 months in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment. This appointment also requires a Research Passport application.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.


Informal enquiries should be emailed to Dr. Robert Semple: or Dr. Gemma Brierley: Metabolic Research Laboratories, Level 4 Wellcome Trust-MRC Institute of Metabolic Science, Box 289, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0QQ

Please quote reference RG11928 on your application and in any correspondence about this vacancy.

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