Applications are invited for a highly motivated postdoctoral research scientist to join the research groups of Dr. Ana Cvejic at the University of Cambridge, Department of Haematology (http://www.haem.cam.ac.uk/staff/senior-staff/dr-ana-cvejic/). The group is based at the Wellcome Trust Sanger Institute.
Blood stem cells need to both perpetuate (self-renew) themselves and differentiate into all mature blood cells to maintain blood formation throughout life. However, it is unclear how the underlying gene regulatory network maintains this population of self-renewing and differentiating stem cells, and how it accommodates the transition from a stem cell to a mature blood cell. Clarifying how HSCs differentiate into diverse cell types is important for understanding how this process is subverted in the generation of blood pathologies.
The aim of my group is to bridge this knowledge gap by providing a method in a relevant model organism (zebrafish, Danio rerio) that will allow us to dissect the role of novel blood genes and to determine their hierarchical position in regulatory networks that underlie haematopoiesis. The work will involve a number of molecular biology techniques in particular single cell transcriptomics and cell biology techniques.
The post holder will have a PhD (or equivalent) with significant knowledge of molecular and cell biology. Knowledge or interest in the field of haematology and/or stem cell biology would be advantageous. As well as being able to demonstrate independent, critical thinking and improve skills in an outstanding research environment.
The position is funded by ERC.
Bhavni Sharma is responsible for the recruitment for this post and can be contacted at email@example.com.
Fixed-term: The funds for this post are available for 36 months in the first instance.
Once an offer of employment has been accepted, the successful candidate will be required to undergo a a health assessment and basic disclosure (criminal records check) check and a security check.
To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.
Please ensure that you upload a covering letter and CV in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.
Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.
The closing date for applications is the 7th of May 2017 with interviews yet to be confirmed by the department.
Please quote reference RB11915 on your application and in any correspondence about this vacancy.
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