A postdoctoral position is available in the group of Ben Luisi in the Department of Biochemistry of the University of Cambridge in Central Cambridge, to work on RNA mediated gene regulation in bacteria. (Bandyra et al. (2012) Mol Cell; Strahl et al. (2015) PLoS Genetics; Dimastrogiovanni et al. (2014) eLife). A multi-disciplinary approach involving biochemical, biophysical and cellular experiments will be used to elucidate the molecular mechanisms of regulatory RNA recognition and action to modulate gene expression. The ultimate goal of the project is to advance our understanding of RNA based regulation, by means of biochemical reconstitution and structural characterisation using purified protein components.
Candidates will hold or about to be awarded a PhD in Biochemistry, Biophysics or Molecular Biology and must have a proven track record of research achievements. Previous experience in the analysis of multi-protein complexes and protein-RNA interactions, as well as familiarity with biophysical techniques such as X-ray crystallography, electron microscopy and single-particle analysis would be an advantage. The position would also be suitable for candidates trained in cellular biology and with an interest in the study of molecular mechanisms in vivo.
Applicants should submit a CV with list of relevant publications, a cover letter explaining why they are suitable for the position and the contact details of at least two referees.
Informal queries can be made to Ben Luisi (firstname.lastname@example.org).
Fixed-term: The funds for this post are available for 36 months in the first instance.
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Please quote reference PH11907 on your application and in any correspondence about this vacancy.
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