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Head of Bioinformatics, Wellcome Trust-MRC Institute of Metabolic Science (Fixed Term)

We are seeking a Head of Bioinformatics to lead the Metabolic Research Laboratories (MRL) Bioinformatics Core Facility, a scientifically complex service providing support to a wide range of researchers within the MRL and potentially across the wider scientific community in Cambridge and nationally. The service involves bioanalytical input into experimental design, technical support, intellectual input for data analysis, optimisation and technological innovation. You will work with the Director to build the capacity in bioinformatics that will be required to support the relevant programmes of PIs in the MRL.

This senior position provides abundant opportunity for a talented and driven bioinformatics scientist to play a leadership role in developing and enhancing the scientific programmes of the Metabolic Research Laboratories and MRC Metabolic Diseases Unit (MDU), at the Wellcome Trust-MRC Institute of Metabolic Science. You will establish strong links with the local bioinformatics community, including the European Bioinformatics Institute and the Sanger Institute, and initiate collaborative interactions and joint projects with MedImmune who provide part of the financial support for this position.

Key Responsibilities:

  • Responsible for the overall performance, budget, and future development of the service.
  • Develop and manage a growing Core support team that ensures institute scientists have the cutting edge tools and support they need to be able to analyse large datasets
  • To lead a growing team of scientists, informing, training and coaching members of staff at all levels.
  • To have a leading role in our collaborative relationship with bioinformaticists at MedImmune
  • To make strategic links with the broader bioinformatics community on the Cambridge Biomedical Campus.
  • To develop own independent programme of research, including seeking grant funding to pursue independent research and to publish innovative science as a lead investigator

Essential Criteria:

  • B.S. degree in Bioinformatics, Computational Biology, Data Science, Computer Science, Information Management or related field. Advanced degree (Ph.D. or equivalent) in Bioinformatics, Computational Biology, Systems Biology or related field.
  • Substantial knowledge of informatics tools and visualization/data mining packages (e.g. Spotfire, IPA, Metacore, ArrayStudio, R, MatLab, GEO, genome visualization packages/browsers) and aptitude for adapting to complex new analysis packages and using them to their full potential.
  • Proficiency in common programming/scripting languages (e.g. SQL, R, Python, Perl, JAVA) and their application in biomedical research
  • Proven record of working with biomedical researchers to develop and apply informatics solutions, skills, and tools.
  • Proven knowledge and skills in analysis and interpretation of large, complex data sets and direct experience in development and implementation of large-scale biological databases.
  • Excellent written and aural communications skills with ability to engage and communicate with people from multiple clinical and biological disciplines, including ability to deliver training to non-experts.
  • Demonstrable scientific knowledge of cell biology, molecular biology or immunology as related to scientific research and development
  • Ability to communicate effectively in formal presentations and small group meetings.
  • Proven record of publication of bioinformatics or systems biology results in peer-reviewed journals.

Fixed-term: The funds for this post are available for 3 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.


Informal enquiries can be made to Steve O'Rahilly, Metabolic Research Laboratories, Level 4, Wellcome Trust-MRC Institute of Metabolic Science, Box 289 Addenbrooke's Hospital, Cambridge CB2 0QQ Email:

Please quote reference RG11835 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Further information

Apply online