A short term post-doctoral research position is available within the Department of Plant Sciences to work on the Chlamydomonas photosynthetic carbon concentrating mechanism (CCM) with Professor Howard Griffiths in the Physiological Ecology Group. Induction of the CCM occurs following transfer of cells from high to ambient CO2 concentrations. We hope to identify key components and regulatory processes which facilitate inorganic carbon transport for Rubisco, which also becomes aggregated into a starch-bound microcompartment, known as the pyrenoid.
The project is part of a collaborative programme between Princeton (formerly Stanford), Edinburgh and JIC Norwich, and is part of the Photosynthesis Ideas Lab programme CAPP2 (Combining Algal and Plant Photosynthesis), funded by BBSRC UK and NSF.
Our current interests are focussed on characterising the physiological function of genes found to be associated with induction of the CCM, and associated with either active inorganic carbon transport or chloroplast pyrenoid formation. Some have been identified from an insertional mutagenesis screen undertaken by our US colleagues. Additional elements also involve more detailed analysis of mutants lacking a pyrenoid, or with mis-localised pyrenoids, in order to determine the associated structural elements required for pyrenoid formation and CCM expression.
Expertise is required in microbial molecular biology, gene expression analysis and protein purification, with knowledge of methods for assessing post-translational modification also preferable. This position can be filled by an appropriate candidate at research assistant or research associate level, depending on relevant qualifications and experience. Appointment at research associate level is dependent on having a PhD (or equivalent experience). Where a PhD has yet to be awarded appointment will initially be made as a research assistant and amended to research associate when the PhD is awarded.
Contact: Howard Griffiths email@example.com; http://www.plantsci.cam.ac.uk/research/howardgriffiths.html Fixed-term: The funds for this post are available until 28 February 2018 in the first instance.
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